Unintentional Overdoses: Understanding the Fentanyl Landscape and Reducing Harm
You can’t overdose just by touching fentanyl pills and powders. Some opioids may be prescribed by a doctor; others are manufactured and sold illegally. Speaking with NPR in September, Gupta called for more funding for addiction treatment and health care services in those communities. “There is no way we’re https://lightgoldenrodyellow-sandpiper-394839.hostingersite.com/2022/03/21/understanding-alcohol-and-our-immune-system/ going to beat this epidemic by not focusing on communities that are often marginalized, underserved, and communities of color,” he said. Additionally, in July/August following the end of a given data year, the NVSS mortality file is ‘closed’ in order to review and prepare the data for production of the historical and public use files and reports.

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As a result, rates of drug overdose deaths presented in this report are not adjusted for race and Hispanic-origin misclassification on death certificates. Some fentanyl analogs are legally manufactured for medical purpose like treating severe pain in humans and sedating animals. Others (such as illicitly manufactured carfentanil) are illegally produced for non-medical use. When used, illicit fentanyl analogs pose severe health risk, including rapid onset opioid overdose. The CDC tracks drug overdose data with the International Classification of Diseases, 10th Revision (ICD-10), which records fentanyl overdose deaths together with those caused by other synthetic opioids. Drug overdose deaths may involve multiple drugs, so a single death might be included in more than one ICD-10 category.
Fentanyl deaths reached a record high in 2022.
- The increase is relatively small — about 300 additional fatalities nationwide over two years — but Dasgupta said it’s an area of concern that needs more study to determine why.
- Illegal fentanyl often comes as a powder or pressed into a pill.
- Naloxone functions as an opioid antagonist by binding to opioid receptors in the brain, thereby reversing and blocking the effects of opioids like fentanyl.
- In 2022, the advocacy group Facing Fentanyl designated Aug. 21 “National Fentanyl Prevention and Awareness Day,” to honor the people who have died from fentanyl and to increase public awareness of its toll.
Therefore, it’s crucial that the person is taken to the hospital immediately after naloxone is administered. Back on the street, Elena and Vadim agreed that while fewer people are dying, the drugs they use often leave them dangerously ill. “In some ways, counting bodies is easier than counting the amount of trauma and infections and other harms that people are experiencing from an unregulated drug supply,” Dasgupta said. Statewide in Pennsylvania, drug deaths are down roughly a third from the peak.
How can a person be sure that they’re taking real fentanyl?
Fentanyl’s emergence represents the latest and most lethal phase of a decades-long public health disaster. The researchers asked the respondents to describe what happened during a suspected fentanyl overdose. Injecting fentanyl was the most common way that a person overdosed on the drug, accounting for 75 Drug rehabilitation percent of the overdoses witnessed, according to the respondents. The remaining 25 percent of the overdoses resulted from people snorting the dug, the researchers said.
- Hypoxia can lead to a coma, permanent brain damage, and even death.
- The shift to synthetic drugs like fentanyl represents a fundamental and likely permanent change in the cartels’ business model.
- Drug overdose deaths may involve multiple drugs; therefore, a single death might be included in more than one category when describing the number of drug overdose deaths involving specific drugs.
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Fentanyl’s Impact on Hispanic Americans

Third, ED data quality and completeness, including demographic data, vary by facility. Fourth, this dataset only captures nonfatal overdoses treated in EDs and might not represent persons who overdose in community settings and are not transported to an ED. Fifth, there could be a small number of fatal overdoses in this study; approximately 1% of fentanyl-involved overdose ED visits in this study were marked as ending in death. The age-adjusted rate for drug overdose deaths involving synthetic opioids other than methadone decreased from 2022 to 2023, the first such decrease since the large increases that began in 2013. The rate also decreased for deaths involving natural and semisynthetic opioids and heroin between 2022 and 2023. For the same period, rates increased for drug overdose deaths involving psychostimulants and cocaine, and rates stayed the same for deaths involving methadone.
“Illegally made fentanyl is often mixed into other drugs without the user knowing, increasing the risk of accidental death,” he explains. On August 31, International Overdose Awareness Day, we all have a chance to learn about opioid overdose and how to prevent it. It’s also an opportune moment to educate ourselves about the role of fentanyl as the main driver of the current stage of the opioid crisis in the United States, why the drug is so dangerous and what we can do to mitigate its dangers. The decline in overdose deaths on Staten Island follows years of multi-pronged efforts by the task force representing a wide range of government agencies, nonprofit groups and health organizations combatting the drug crisis. This table describes the data quality for all jurisdictions by year, month, and period (with all jurisdictions included by default).
The third and current wave began in 2013, defined by a catastrophic rise in overdose deaths involving synthetic opioids, overwhelmingly driven by IMF. Opioid addiction remains a major public health crisis, with millions affected and close to 100,000 opioid overdose deaths reported annually, although there have been small improvements in overall deaths. The timeliness of provisional mortality surveillance data in the National Vital Statistics System (NVSS) database varies by cause of death.
How Do Opioids Affect the Body?
Thus, the therapeutic approach should continue until a normal respiratory rate coincides with appropriate oxygen saturation levels. Fentanyl is a powerful pain medicine made in a lab (synthetic opioid). Illegal fentanyl is often mixed how long does fentanyl stay in your system into street drugs like heroin, cocaine, and meth. Or it may be added to fake pills made to look like prescription medicines.
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The reported provisional counts can be multiplied by this factor to generate a set of predicted provisional counts that adjust for reporting delays. Drug overdoses are one of the leading causes of injury death in adults and have risen over the past several decades in the United States (1–3). Overdoses involving synthetic opioids (fentanyl, for example) and stimulants (cocaine and methamphetamine, for example) have also risen in the past few years (1). While the numbers remain catastrophically high, the most recent data from the CDC’s National Center for Health Statistics for 2023 showed the first signs of a potential plateau. The overall number of drug overdose deaths decreased by 4% from 2022 to 2023, and the rate of deaths involving synthetic opioids specifically saw a slight decrease of about 2%.